Single cell transcriptomic signatures of normal human newborn, child and adult lungs

Xin Sun¹, Allen Wang¹, Sebastian Preissl¹, Kyle Gaulton¹, Jamie Verheyden¹, Minzhe Guo², Ravi Misra³, Gloria Pryhuber³, Jeffrey A. Whitsett², Yan Xu²

¹University of California, San Diego, ²Cincinnati Children's Hospital Medical Center, ³University of Rochester Medical Center, ^*Corresponding author

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Description Single cell transcriptomic signatures of normal human newborn, child and adult lungs

Dataset ID LMEX0000004388

Assay Type Single-cell RNA-seq

Organism Human

Stages Neonate | Child | Adult

Cell Count 46500

Technology 10x Genomics Chromium Single Cell Gene Expression

Reference Wang et al. (2020)

External databases GEO: GSE161383

File	Description	Size
Cell Metadata	Cell metadata	644.0 KB
Counts Matrix	Raw counts matrix	84.0 MB
LMEX0000004388.h5ad	HDF5 annotated format single-cell data matrix	668.6 MB
Scaled Counts Matrix	Scaled counts matrix	560.0 MB
UMAP Coordinates	UMAP coordinates	1.0 MB

LungMAP ID	Alt ID	Species	Sex	Race	Age	Age Group	GA at Birth	CGA	Weight	Weight Percentile	Cause of Death	Type of Death
LMSP0000000153	D032	Homo sapiens	Male	White	3 years	Child	40 weeks		18.14 kg	92	Trauma - Isolated Head Trauma	DBD (after brain death)
LMSP0000000167	D046	Homo sapiens	Male	White	3 years	Child	40 weeks		15 kg	64	Trauma - Auto Accident	DCD (circulatory death)
LMSP0000000183	D062	Homo sapiens	Male	White	4 days	Neonate	31 weeks, 4 days	32 weeks	2.615 kg	98	Congenital Anomaly - Brain	DCD (circulatory death)
LMSP0000000209	D088	Homo sapiens	Female	White	1 days	Neonate	31 weeks, 3 days	31.43 weeks			Congenital Anomaly - Brain	DCD (circulatory death)
LMSP0000001029	D122	Homo sapiens	Male	Unknown or Not Reported	31 years	Adult			109 kg		Trauma - Fall from Height	DBD (after brain death)
LMSP0000001046	D139	Homo sapiens	Female	White	3 years	Child	40 weeks		23.9 kg	99	Trauma - Auto Accident	DBD (after brain death)
LMSP0000001056	D150	Homo sapiens	Male	White	1 days	Neonate	29 weeks	29 weeks	0.959 kg	17	Congenital Anomaly - Brain	DCD (circulatory death)
LMSP0000001081	D175	Homo sapiens	Female	White	29 years	Adult			89.1 kg		Trauma - Firearm	DCD (circulatory death)
LMSP0000001119	D231	Homo sapiens	Female	African American	33 years	Adult			103.87 kg		Anoxic/Hypoxic Brain Injury - Other	DCD (circulatory death)

7 of this study's 9 samples were also assayed by 118 other LungMAP studies, across 5 modalities. Click any node to list those studies. The other 2 appear in no other study and are not drawn.

Shared samples by study