Respiratory Airway Secretory Cells in COPD
Maria C. Basil1, Fabian L. Cardenas-Diaz1, Jaymin J. Kathiriya2, Michael P. Morley1, Justine Carl1, Alexis N. Brumwell2, Jeremy Katzen1, Katherine J. Slovik1, Apoorva Babu3, Su Zhou1, Madison M. Kremp1, Katherine B. McCauley4, Shanru Li1, Joseph D. Planer1, Shah S. Hussain5, Xiaoming Liu6, Rebecca Windmueller7, Yun Ying1, Kathleen M. Stewart1, Michelle Oyster1, Jason D. Christie1, Joshua M. Diamond1, John F. Engelhardt6, Edward Cantu3, Steven M. Rowe5, Darrell N. Kotton4, Harold A. Chapman2, Edward E. Morrisey1
1Perelman School of Medicine, University of Pennsylvania, 2University of California, San Francisco, 3Penn-Children’s Hospital of Philadelphia Lung Biology Institute, 4Boston University, 5University of Alabama at Birmingham, 6University of Iowa, 7Children’s Hospital of Philadelphia, *Corresponding author
Aberrant basaloid cell COPD vs Control DEGsAberrant basaloid cell marker genesAdventitial fibroblast COPD vs Control DEGsAdventitial fibroblast marker genesAirway basal marker genesAirway smooth muscle marker genesAlveolar duct myofibroblast (contractile) COPD vs Control DEGsAlveolar duct myofibroblast (contractile) marker genesAlveolar epithelial transitional (AT2-AT1) COPD vs Control DEGsAlveolar epithelial transitional (AT2-AT1) marker genesAlveolar fibroblast COPD vs Control DEGsAlveolar fibroblast marker genesAlveolar macrophage (lipid homeostatic) marker genesAlveolar macrophage COPD vs Control DEGsAlveolar macrophage marker genesAlveolar type 1 COPD vs Control DEGsAlveolar type 1 marker genesAlveolar type 2 COPD vs Control DEGsAlveolar type 2 cell proliferating marker genesAlveolar type 2 marker genesB COPD vs Control DEGsB marker genesCD141+ conventional dendritic cell (cDC1) COPD vs Control DEGsCD141+ conventional dendritic cell (cDC1) marker genesCD4+, alpha-beta T COPD vs Control DEGsCD4+, alpha-beta T marker genesCD4+, regulatory T COPD vs Control DEGsCD4+, regulatory T marker genesCD8+, alpha-beta T COPD vs Control DEGsCD8+, alpha-beta T marker genesCOPD airway marker genesCapillary 1 marker genesCapillary 2 COPD vs Control DEGsCapillary 2 marker genesCapillary intermediate 1 marker genesCapillary intermediate 2 marker genesClassical monocyte COPD vs Control DEGsClassical monocyte marker genesClub (Bronchioles) COPD vs Control DEGsClub (Bronchioles) marker genesClub (Trachea & Bronchus) marker genesCycling lymphatic endothelial cell of lung marker genesDeuterosomal cell COPD vs Control DEGsDeuterosomal cell marker genesDuct, basal marker genesDuct, secretory marker genesErythrocyte marker genesGoblet marker genesGroup 1 ILC marker genesHematopoietic stem cell COPD vs Control DEGsHematopoietic stem cell marker genesHillock basal marker genesHillock squamous COPD vs Control DEGsHillock squamous marker genesInflammatory alveolar fibroblast marker genesInterstitial fibroblast marker genesInterstitial macrophage COPD vs Control DEGsInterstitial macrophage marker genesLangerhans cell marker genesLipofibroblast 1 marker genesLymphatic endothelial marker genesMast cell COPD vs Control DEGsMast cell marker genesMegakaryocyte marker genesMesothelial COPD vs Control DEGsMesothelial marker genesMetallothionein+ AM marker genesMigratory lung dendritic cell marker genesMucous marker genesMulticiliated (Bronchioles) marker genesMulticiliated (Trachea & Bronchus) marker genesMulticiliated (axonemal) COPD vs Control DEGsMulticiliated (axonemal) marker genesMyoepithelial marker genesNK marker genesNasal club cell COPD vs Control DEGsNasal club cell marker genesNasal goblet cell COPD vs Control DEGsNasal goblet cell marker genesNasal serous cell COPD vs Control DEGsNasal serous cell marker genesNeutrophil marker genesNon-classical monocyte marker genesPeribronchial fibroblast COPD vs Control DEGsPeribronchial fibroblast marker genesPericytes marker genesPlasma COPD vs Control DEGsPlasma marker genesPlasmacytoid dendritic cell COPD vs Control DEGsPlasmacytoid dendritic cell marker genesProliferating AM marker genesPulmonary alveolar duct myofibroblast marker genesPulmonary arteriole endothelial marker genesPulmonary artery endothelial marker genesPulmonary capillary endothelial marker genesPulmonary ionocyte marker genesPulmonary neuroendocrine cell COPD vs Control DEGsPulmonary neuroendocrine cell marker genesPulmonary vein endothelial COPD vs Control DEGsPulmonary vein endothelial marker genesRASC COPD vs Control DEGsRASC marker genesSchwann cell marker genesSecondary crest myofibroblast marker genesSerous (bronchial) marker genesSmooth muscle lymphatic COPD vs Control DEGsSmooth muscle lymphatic marker genesSubpleural fibroblast COPD vs Control DEGsSubpleural fibroblast marker genesSystemic artery endothelial COPD vs Control DEGsSystemic artery endothelial marker genesSystemic venous endothelial (activated) marker genesSystemic venous endothelial marker genesT cell proliferating COPD vs Control DEGsT cell proliferating marker genesTransitioning monocyte-derived macrophage COPD vs Control DEGsTransitioning monocyte-derived macrophage marker genesTuft COPD vs Control DEGsTuft marker genesVascular smooth muscle (contractile) marker genesVascular smooth muscle marker genesiNKT marker genes
Gene symbols or identifiers, one per line.
COPD airway marker genes
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