LungMAP - Omics

Single cell transcriptomic signatures of normal human newborn, child and adult lungs

Xin Sun^1*, Allen Wang¹, Sebastian Preissl¹, Kyle Gaulton¹, Jamie Verheyden¹, Minzhe Guo², Ravi Misra³, Gloria Pryhuber³, Jeffrey A. Whitsett², Yan Xu²

¹University of California, San Diego, ²Cincinnati Children's Hospital Medical Center, ³University of Rochester Medical Center, ^*Corresponding author

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Description

Single cell transcriptomic signatures of normal human newborn, child and adult lungs

LungMAP ID: LMEX0000004388

Organism: human

Stages: neonate | child | adult

Assay type: Single-cell RNA-seq

Technology: 10x Genomics Chromium Single Cell Gene Expression

Reference: Wang et al. (2020)

External databases:

LungMAP ID	Alt ID	Species	Sex	Race	Age	Age Group	GA at Birth	CGA	Weight	Weight Percentile	Cause of Death	Type of Death	Health Status
LMSP0000000153	D032	Homo sapiens	Male	White	3 years	Child			18.14 kg	92	Trauma	DBD (after brain death)	No known lung disease
LMSP0000000167	D046	Homo sapiens	Male	White	3 years	Child			15 kg	44	Trauma	DCD (circulatory death)	No known lung disease
LMSP0000000183	D062	Homo sapiens	Male	Unknown or Not Reported	4 days	Neonate	31 weeks, 4 days	32.43 weeks	2.615 kg	99	Congenital Anomaly	DCD (circulatory death)	Known lung disease
LMSP0000000209	D088	Homo sapiens	Female	Unknown or Not Reported	1 day	Neonate	31 weeks, 3 days	31.86 weeks	kg	0	Congenital Anomaly	DCD (circulatory death)	No known lung disease
LMSP0000001029	D122	Homo sapiens	Male	Unknown or Not Reported	31 years	Adult			109		Trauma	DBD (after brain death)	No known lung disease
LMSP0000001046	D139	Homo sapiens	Female	White	3 years	Child			23.9	100	Trauma	DBD (after brain death)	No known lung disease
LMSP0000001056	D150	Homo sapiens	Male	White	1 day	Neonate	29 weeks, 0 days		0.96	17	Congenital Anomaly	DCD (circulatory death)	No known lung disease
LMSP0000001081	D175	Homo sapiens	Female	White	29 years	Adult			89.1		Trauma	DCD (circulatory death)	No known lung disease
LMSP0000001119	D231	Homo sapiens	Female	African American	33 years	Adult			103.87		Anoxic/Hypoxic Brain Injury	DCD (circulatory death)	Known lung disease

File	Description	Size
Cell Metadata	Cell metadata	644.0 KB
Counts Matrix	Raw counts matrix	84.0 MB
LMEX0000004388.h5ad	HDF5 annotated format single-cell data matrix	668.6 MB
Scaled Counts Matrix	Scaled counts matrix	560.0 MB
UMAP Coordinates	UMAP coordinates	1.0 MB